Five Supplements You’re Not Taking

Marie Parks

Ever wonder if there are supplements you’re not taking but should be? Regardless of what may be already in your regimen, a number of these may be worth adding into your daily mix.

A common "baseline" supplement regimen consists of a multivitamin, fish oil, vitamin D and CoQ10. And all those are super important, but they’re merely the foundation of an ideal health plan.

So here’s a list of five supplements you’re probably not taking but should definitely consider.

AMPK Activators

Two plant extracts, Gynostemma Pentaphyllum and trans-tiliroside, activate the enzyme AMPK (adenosine monophosphate-activated protein kinase).1,2

When activated, AMPK has several effects such as turning off signals that cause age-related damage (resulting in vitality and a longer life span),3 decreasing fat storage,4 5,6 producing new mitochondria for increased energy,7 and helping to support blood sugar and cholesterol levels already within normal range.8,9,10

Pine Bark Extract

Pine bark extract contains beneficial procyanidins and bioflavonoids that act on various aspects of health!

Pine bark extract provides beauty from within by rejuvenating skin hydration and pigmentation.11,12,13 It also helps support healthy and normal blood pressure14,15 and blood sugar,16,17 and has been shown to promote healing from diabetic complications eye and skin issues.18,19 Furthermore, pine bark extract not only helps shield brain cells from damage, but it also can help with memory and attention!20

PS (Phosphatidylserine)

Being a large component of brain tissue, PS is necessary for healthy cell and neural function. More specifically, it supports nerve cell membranes in the brain for optimal focus and recall.21

The brain-supporting ability of PS may be particularly beneficial in children with ADHD as it has been shown to mitigate some of the symptoms such as lack of attention and short-term memory.22Additionally, PS promotes a better mood and aids in stress management!23

Nicotinamide Riboside

Nicotinamide adenine dinucleotide (NAD+) is found in every cell in your body and helps to enhance youthfulness and longevity by activating sirtuins.24

Sirtuin activation has numerous health benefits such as modulating metabolism and favorably reducing fat storage,25,26 supercharging energy and endurance by helping release fuel from glucose,27 and reducing amyloid plaque build-up associated with Alzheimer’s disease.28

Nicotinamide riboside is a patented ingredient that has been shown to help increase cellular levels of NAD+ in the body. 29,30


Chlorophyllin is a mixture of sodium copper salts that is derived from chlorophyll. It has various cell-protecting properties, which are important as we are exposed to environmental toxins on a daily basis.

Chlorophyllin has exhibited the ability to bind to and help rid the body of dangerous toxins31,32 and protect organs like the liver against damage from fungal toxins such as aflatoxin.33, 34

In regards to cellular function, chlorophyllin triggers abnormal cells to die off (apoptosis),35 inhibits unhealthy cells from spreading by activating E-cadherin,36 and reduces tumor formation by decreasing blood flow to dangerous cells.37

Chlorophyllin can also help maintain a normal white blood cell count and boost immune function.38

The Bottom Line

Some of you might be taking some — or all — of these supplements. Great! Hopefully we’ve reiterated their importance. For those who aren’t taking them, hopefully we’ve conveyed the benefits you can get from them.

Of course, everyone has a unique biochemistry, as well as different health concerns and goals, so you have to ask yourself what these are and then look at what combination of nutrients best supports them.

Don’t forget! If you need help figuring out a regimen that is most appropriate, feel free to call our Health Advisors for free at 1-800-226-2370.


  1. Bioorg Med Chem. 2011 Nov 1;19(21):6254-60.
  2. J Nutr Biochem. 2012 Jul;23(7):768-76.
  3. J Mol Med (Berl). 2011 Jul;89(7):667-76.
  4. J Lipid Res. 2006 Jun;47(6):1281-8.
  5. Future Oncol. 2010 Mar;6(3):457-70.
  6. Diabetes. 2004 Sep;53(9):2242-9.
  7. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15983-7.
  8. Mol Cell Endocrinol. 2013 Feb 25;366(2):204-14.
  9. Biochem J. 2003 Oct 1;375(Pt 1):1-16.
  10. Physiol Rev. 2009 Jul;89(3):1025-78.
  11. Photochem Photobiol. 2004 Feb;79(2):193-8.
  12. J Dermatolog Treat. 2004 Jul;15(4):222-6.
  13. Phytother Res. 2002 Sep;16(6):567-71.
  14. Nutr Res. 2008 May;28(5):315-20.
  15. Hypertension. 2010 Jun;55(6):1373-80.
  16. Phytother Res. 2010 Aug;24(8):1242-9.
  17. Diabetes Care. 2004 Mar;27(3):839.
  18. J Ocul Pharmacol Ther. 2009 Dec;25(6):537-40.
  19. Angiology. 2006 Aug-Sep;57(4):431-6
  20. J Psychopharmacol. 2008 Jul;22(5):553-62.
  21. Nutrition. 2015 Jun;31(6):781-6.
  22. J Hum Nutr Diet. 2014 Apr;27 Suppl 2:284-91.
  23. Nutr Neurosci. 2001;4(3):169-78.
  24. Pharmacol Rev. 2012 Jan;64(1):166-87.
  25. Trends Endocrinol Metab. 2014 Mar;25(3):138-45
  26. Int J Biol Sci. 2011;7(5):575-87. Epub 2011 May 9.
  27. Cell Metab. 2012 Jun 6;15(6):838-47.
  28. Neurobiol Aging. 2013 Jun;34(6):1581-8
  29. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):657-61.
  30. EMBO Mol Med. 2014 Apr 6;6(6):721-31.
  31. Mutat Res. 2003 Feb-Mar;523-524:209-16.
  32. Mutat Res. 1994 Jul 16;308(2):191-203.
  33. Carcinogenesis. 2007 Jun;28(6):1294-302. Epub 2007 Feb 8.
  34. Cancer Prev Res (Phila). 2009 Dec;2(12):1015-22.
  35. Food Chem Toxicol. 2012 Mar;50(3-4):867-76.
  36. J Nutr. 2004 Dec;134(12 Suppl):3441S-3444S.
  37. Cell Oncol (Dordr). 2012 Oct;35(5):385-95.
  38. Chin J Integr Med. 2005 Dec;11(4):279-82.


Adeyinka Adegbeminiyi said...

WPls, what exactly are the supplements, if one wants to buy them in the store?

Life Extension said...

Adeyinka Adegbeminiyi- Unfortunately, we can't discuss products we sell on this post. However, please feel free to call us at 1-800-226-2370 for more info. :)

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