The Power of CoQ10

The fact that CoQ10 is involved in the prevention of so many conditions is no surprise. Coenzyme Q10 is present in every cell of your body. Its ubiquitous nature even gave rise to its other names: ubiquinone and ubiquinol

Coenzyme Q10 (CoQ10) may help to protect against a number of conditions, including heart failure, cardiac arrhythmias, cardiomyopathy, Parkinson's disease, Gulf War illness, septic shock, Huntington's disease, inflammation, breast cancer, chronic fatigue syndrome, depression, fibromyalgia, ataxia, and autism.1-18

It's been successful in relieving depression and fatigue in multiple sclerosis, has improved blood sugar control in diabetics, and also shows promise for male infertility.20-22

CoQ10 Increases Cellular Energy

Coenzyme Q10's role in the production of energy within the cells' mitochondria means it’s something we can't live without. CoQ10 helps to generate adenosine triphosphate (ATP), the molecule dubbed "the energy currency of life."

The greatest concentrations of CoQ10 can be found in organs that have a high energy requirement, such as the heart. Accordingly, some of the most significant benefits of the compound, including a reduction in death,23 have been seen in heart failure patients.1

In fact, higher blood levels of CoQ10 were found to improve survival in a group of heart failure patients over a period of up to five years.3

Statins Reduce CoQ10 Levels

Research shows statins, cholesterol-reducing drugs, lower CoQ10 levels.24 An Italian study found a 40% decline in CoQ10 levels in patients treated with pravastatin or simvastatin.25 Similarly, research showed decreased levels of CoQ10 within two weeks of beginning treatment with atorvastatin.26

Although the results of trials involving CoQ10 supplementation in statin-induced muscle pain have been mixed, a study reported last year found significant improvement in muscle pain in 75% of statin-treated patients who received coenzyme Q10.27

Another study found that pain levels and muscle weakness were reduced in CoQ10-treated men and women with statin-related muscle problems.28

CoQ10 Reduces Oxidative Stress and Extends Life

Coenzyme Q10 has significant antioxidant properties.29 This reduction in oxidative stress may be the mechanism involved in its ability to extend life in worms known as C. elegans.30

Coenzyme Q10 supplementation has also been associated with a greater life span in rats, in addition to lower levels of DNA damage.31

Choosing the Right CoQ10 Supplement

With aging, levels of CoQ10 naturally decline, making supplementation a wise choice. Coenzyme Q10 is available as ubiquinone or ubiquinol.

Research involving ubiquinol shows it is much better absorbed than ubiquinone, resulting in greater benefits. Due to its chemical nature, coenzyme Q10 is best taken with a fat-containing meal for optimal absorption.


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  2. Atherosclerosis. 2011 Jun;216(2):395-401. 
  3. J Am Coll Cardiol. 2008 Oct 28;52(18):1435-41. 
  4. J Investig Med. 2015 Jun;63(5):735-739. 
  5. Int J Tissue React. 1990;12(3):169-71. 
  6. Arch Neurol. 2002 Oct;59(10):1541-50. 
  7. See comment in PubMed Commons belowNeural Comput. 2014 Nov;26(11):2594-651. 
  8. Crit Care. 2011 Aug 9;15(4):R189. 
  9. J Huntingtons Dis. 2012 Jan;1(1):65-9. 
  10. Nutrition. 2012 Jul;28(7-8):767-72. 
  11. J Gerontol A Biol Sci Med Sci. 2012 Jan;67(1):3-10. 
  12. Nutr J. 2013 Nov 6;12(1):142. 
  13. Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1124-30. 
  14. Neuro Endocrinol Lett. 2009;30(4):470-6. 
  15. Neuro Endocrinol Lett. 2009;30(4):462-9. 
  16. Clin Biochem. 2012 Apr;45(6):509-11. 
  17. Arch Neurol. 2005 Apr;62(4):621-6. 
  18. Oxid Med Cell Longev. 2014;2014:798957. 
  19. Int J Cardiol. 2013 Sep 1;167(5):1860-6. 
  20. Nutr Neurosci. 2015 Jan 20. 
  21. Minerva Gastroenterol Dietol. 2013 Jun;59(2):231-6. 
  22. J Urol. 2009 Jul;182(1):237-48. 
  23. JACC Heart Fail. 2014 Dec;2(6):641-9. 
  24. Proc Natl Acad Sci U S A. 1990 Nov;87(22):8931-4. 
  25. J Clin Pharmacol. 1993 Mar;33(3):226-9. 
  26. Arch Neurol. 2004 Jun;61(6):889-92. 
  27. Med Sci Monit. 2014 Nov 6;20:2183-8. 
  28. Neuro Endocrinol Lett. 2012;33 Suppl 2:98-101. 
  29. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4879-83. 
  30. Mech Ageing Dev. 2004 Jan;125(1):41-6. 
  31. Exp Gerontol. 2004 Feb;39(2):189-94.


Ros G said...

This is good to know. I just received my CoQ10 order.

Life Extension said...

Ros G- Great! We're glad you enjoyed it!

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